block F5 = Refresh when debugging.

ILSpy/MainWindow.xaml.cs

@@ -297,10 +297,12 @@ namespace ICSharpCode.ILSpy
 		
 		void RefreshCommandExecuted(object sender, ExecutedRoutedEventArgs e)
 		{
-			e.Handled = true;
-			var path = GetPathForNode(treeView.SelectedItem as SharpTreeNode);
-			ShowAssemblyList(assemblyListManager.LoadList(ILSpySettings.Load(), assemblyList.ListName));
-			SelectNode(FindNodeByPath(path, true));
+			if (!DebuggerService.CurrentDebugger.IsDebugging) {
+				e.Handled = true;
+				var path = GetPathForNode(treeView.SelectedItem as SharpTreeNode);
+				ShowAssemblyList(assemblyListManager.LoadList(ILSpySettings.Load(), assemblyList.ListName));
+				SelectNode(FindNodeByPath(path, true));
+			}
 		}
 		
 		void AttachToProcessExecuted(object sender, ExecutedRoutedEventArgs e)