diff --git a/src/Generator.Tests/GeneratorTest.cs b/src/Generator.Tests/GeneratorTest.cs
index 54777fae..20478f58 100644
--- a/src/Generator.Tests/GeneratorTest.cs
+++ b/src/Generator.Tests/GeneratorTest.cs
@@ -29,6 +29,7 @@ namespace CppSharp.Utils
             options.OutputDir = Path.Combine(GetOutputDirectory(), "gen", name);
             options.Quiet = true;
             options.GenerateDebugOutput = true;
+            options.GenerateSequentialLayout = true;
             var testModule = options.AddModule(name);
             testModule.SharedLibraryName = $"{name}.Native";
 
diff --git a/src/Generator/Generators/CSharp/CSharpSources.cs b/src/Generator/Generators/CSharp/CSharpSources.cs
index f1376ddb..3731cf3d 100644
--- a/src/Generator/Generators/CSharp/CSharpSources.cs
+++ b/src/Generator/Generators/CSharp/CSharpSources.cs
@@ -531,19 +531,24 @@ namespace CppSharp.Generators.CSharp
 
         public void GenerateClassInternals(Class @class)
         {
+            var sequentialLayout = Options.GenerateSequentialLayout && CanUseSequentialLayout(@class);
+
             PushBlock(BlockKind.InternalsClass);
-            if (!Options.GenerateSequentialLayout || @class.IsUnion)
-                WriteLine($"[StructLayout(LayoutKind.Explicit, Size = {@class.Layout.GetSize()})]");
-            else if (@class.MaxFieldAlignment > 0)
-                WriteLine($"[StructLayout(LayoutKind.Sequential, Pack = {@class.MaxFieldAlignment})]");
+
+            if (@class.Layout.GetSize() > 0)
+            { 
+                var layout = sequentialLayout ? "Sequential" : "Explicit";
+                var pack = @class.MaxFieldAlignment > 0 ? $", Pack = {@class.MaxFieldAlignment}" : string.Empty;
+                WriteLine($"[StructLayout(LayoutKind.{layout}, Size = {@class.Layout.GetSize()}{pack})]");
+            }
 
             GenerateClassInternalHead(@class);
             WriteOpenBraceAndIndent();
 
             TypePrinter.PushContext(TypePrinterContextKind.Native);
 
-            foreach (var field in @class.Layout.Fields)
-                GenerateClassInternalsField(field, @class);
+            GenerateClassInternalsFields(@class, sequentialLayout);
+
             if (@class.IsGenerated)
             {
                 var functions = GatherClassInternalFunctions(@class);
@@ -764,24 +769,71 @@ namespace CppSharp.Generators.CSharp
                 Write(" : {0}", string.Join(", ", bases));
         }
 
-        private void GenerateClassInternalsField(LayoutField field, Class @class)
+        private bool CanUseSequentialLayout(Class @class)
         {
-            TypePrinterResult retType = TypePrinter.VisitFieldDecl(
-                new Field { Name = field.Name, QualifiedType = field.QualifiedType });
+            if (@class.IsUnion)
+                return false;
 
-            PushBlock(BlockKind.Field);
+            var fields = @class.Layout.Fields;
 
-            if (!Options.GenerateSequentialLayout || @class.IsUnion)
-                WriteLine($"[FieldOffset({field.Offset})]");
-            Write($"internal {retType}");
-            if (field.Expression != null)
-            {
-                var fieldValuePrinted = field.Expression.CSharpValue(ExpressionPrinter);
-                Write($" = {fieldValuePrinted}");
+            if (fields.Count > 1)
+            { 
+                for (var i = 1; i < fields.Count; ++i)
+                {
+                    if (fields[i].Offset == fields[i - 1].Offset)
+                        return false;
+                }
             }
-            WriteLine(";");
 
-            PopBlock(NewLineKind.BeforeNextBlock);
+            return true;
+        }
+
+        private void GenerateClassInternalsFields(Class @class, bool sequentalLayout)
+        {
+            var fields = @class.Layout.Fields;
+
+            for (var i = 0; i < fields.Count; ++i)
+            {
+                var field = fields[i];
+
+                TypePrinterResult retType = TypePrinter.VisitFieldDecl(
+                    new Field { Name = field.Name, QualifiedType = field.QualifiedType });
+
+                PushBlock(BlockKind.Field);
+
+                if (!sequentalLayout)
+                    WriteLine($"[FieldOffset({field.Offset})]");
+
+                Write($"internal {retType}");
+                if (field.Expression != null)
+                {
+                    var fieldValuePrinted = field.Expression.CSharpValue(ExpressionPrinter);
+                    Write($" = {fieldValuePrinted}");
+                }
+                WriteLine(";");
+
+                // HACK: work around the lack of alignment in StructLayout
+                // it's been requested multiple times to no avail:
+                // https://github.com/dotnet/runtime/issues/5931, https://github.com/dotnet/runtime/issues/9089, https://github.com/dotnet/runtime/issues/22990
+                // Sometimes padding is needed due to aligment.
+                // The linux 32 bit target pads at the end the structure
+                // which is already handled by using [StructLayout(Size = n)].
+                // However the windows 32 bit target pads at the front,
+                // right after the vtable pointer, which is what we are handling here
+                if (sequentalLayout && fields[i].IsVTablePtr)
+                {
+                    var nativePointerSize = Context.TargetInfo.PointerWidth / 8;
+
+                    if (i + 1 < fields.Count)
+                    {
+                        var padding = fields[i + 1].Offset - field.Offset - nativePointerSize;
+                        if (padding > 0 && padding <= @class.Layout.Size)
+                            WriteLine($"internal fixed byte {field.Name}Padding[{padding}];");
+                    }
+                }
+
+                PopBlock(sequentalLayout && i + 1 != fields.Count ? NewLineKind.Never : NewLineKind.BeforeNextBlock);
+            }
         }
 
         private void GenerateClassField(Field field, bool @public = false)
diff --git a/tests/CSharp/CSharp.Tests.cs b/tests/CSharp/CSharp.Tests.cs
index 424fe592..6bde60c9 100644
--- a/tests/CSharp/CSharp.Tests.cs
+++ b/tests/CSharp/CSharp.Tests.cs
@@ -721,8 +721,11 @@ public unsafe class CSharpTests : GeneratorTestFixture
         {
             var independentFields = internalType.GetFields(BindingFlags.Instance | BindingFlags.NonPublic);
             var fieldOffset = (FieldOffsetAttribute) independentFields[0].GetCustomAttribute(typeof(FieldOffsetAttribute));
-            Assert.That(fieldOffset.Value, Is.EqualTo(0));
+            if (fieldOffset != null)
+                Assert.That(fieldOffset.Value, Is.EqualTo(0));
+            Assert.That((int)Marshal.OffsetOf(internalType, independentFields[0].Name), Is.EqualTo(0));
         }
+
         foreach (var internalType in new Type[]
             {
                 typeof(CSharp.TwoTemplateArgs.__Internal_Ptr),
@@ -733,12 +736,21 @@ public unsafe class CSharpTests : GeneratorTestFixture
             var independentFields = internalType.GetFields(BindingFlags.Instance | BindingFlags.NonPublic);
             Assert.That(independentFields.Length, Is.EqualTo(2));
             var fieldOffsetKey = (FieldOffsetAttribute) independentFields[0].GetCustomAttribute(typeof(FieldOffsetAttribute));
-            Assert.That(fieldOffsetKey.Value, Is.EqualTo(0));
+            if (fieldOffsetKey != null)
+                Assert.That(fieldOffsetKey.Value, Is.EqualTo(0));    
+            Assert.That((int)Marshal.OffsetOf(internalType, independentFields[0].Name), Is.EqualTo(0));
             var fieldOffsetValue = (FieldOffsetAttribute) independentFields[1].GetCustomAttribute(typeof(FieldOffsetAttribute));
-            Assert.That(fieldOffsetValue.Value, Is.EqualTo(Marshal.SizeOf(IntPtr.Zero)));
+            if (fieldOffsetValue != null)
+                Assert.That(fieldOffsetValue.Value, Is.EqualTo(Marshal.SizeOf(IntPtr.Zero)));
+            Assert.That((int)Marshal.OffsetOf(internalType, independentFields[1].Name), Is.EqualTo(Marshal.SizeOf(IntPtr.Zero)));
         }
     }
 
+    public void TestClassSize()
+    {
+        Assert.That(Marshal.SizeOf<HasSecondaryBaseWithAbstractWithDefaultArg.__Internal>, Is.EqualTo(Marshal.SizeOf<IntPtr>() * 2));
+    }
+
     [Test]
     public void TestConstantArray()
     {